B16, stimulation of melanin synthesis (basal, pro-pigmenting agents)| Type of assay | Melanin synthesis | | Biological model | B16 melanoma cell line | | Species | Mouse | | Endpoint | Melanin content |
| B16-0001 | Melanogenesis, Pigmentation disorders | Melanin synthesis | B16 melanoma cell line | Mouse | Melanin content | Photometry | Basal | |
NHEK + NHEM, stimulation of melanin synthesis (Basal, pro-pigmenting agents)| Type of assay | Melanin synthesis | | Biological model | Keratinocytes + Melanocytes, coculture | | Species | Human | | Endpoint | Melanin content |
| KM-0001 | Melanogenesis, Pigmentation disorders | Melanin synthesis | Keratinocytes + Melanocytes, coculture | Human | Melanin content | Photometry | Basal | |
NHEK + NHEM, inhibition of melanin synthesis (MSH stimulation, depigmenting molecules)| Type of assay | Melanin synthesis | | Biological model | Keratinocytes + Melanocytes, coculture | | Species | Human | | Endpoint | Melanin content |
| KM-0015 | Melanogenesis, Pigmentation disorders | Melanin synthesis | Keratinocytes + Melanocytes, coculture | Human | Melanin content | Photometry | NDP-MSH | |
NHEM, stimulation of melanin synthesis (Basal, pro-pigmenting agents)| Type of assay | Melanin synthesis | | Biological model | Epidermal melanocytes (NHEM) | | Species | Human | | Endpoint | Melanin content |
| NHEM-0001 | Melanogenesis, Pigmentation disorders | Melanin synthesis | Epidermal melanocytes (NHEM) | Human | Melanin content | Photometry | Basal | |
NHEM, inhibition of melanin synthesis (MSH-induced, whitening agents)| Type of assay | Melanin synthesis | | Biological model | Epidermal melanocytes (NHEM) | | Species | Human | | Endpoint | Melanin content |
| NHEM-0002 | Melanogenesis, Pigmentation disorders | Melanin synthesis | Epidermal melanocytes (NHEM) | Human | Melanin content | Photometry | NDP-MSH | |
RHEm, modulation of melanin synthesis (basal)| Type of assay | Melanin synthesis | | Biological model | Melanocyte-containing reconstructed epidermis, BIOalternatives RHEm | | Species | Human | | Endpoint | Melanin content |
| RHEM-0014 | Melanogenesis, Pigmentation disorders | Melanin synthesis | Melanocyte-containing reconstructed epidermis, BIOalternatives RHEm | Human | Melanin content | Photometry | Basal | |
RHEm, pigmentation (Fontana-Masson staining)| Type of assay | Melanin synthesis | | Biological model | Melanocyte-containing reconstructed epidermis, BIOalternatives RHEm | | Species | Human | | Endpoint | Melanin staining |
| RHEM-0015 | Melanogenesis, Pigmentation disorders | Melanin synthesis | Melanocyte-containing reconstructed epidermis, BIOalternatives RHEm | Human | Melanin staining | Histology (Fontana-Masson staining) | Basal | |
Skin maintained ex vivo, pigmentation (Fontana-Masson staining)| Type of assay | Melanin synthesis | | Biological model | Skin (ex vivo) | | Species | Human | | Endpoint | Melanin staining |
| SKIN-0020 | Melanogenesis, Skin morphology, Pigmentation disorders | Melanin synthesis | Skin (ex vivo) | Human | Melanin staining | Histology (Fontana-Masson staining) | Basal | |
