Online Catalogs
EPIBA-0052 - RHE, testosterone metabolism & 5- alpha reductase activity (basal)
| Type of assay | Androgen metabolism |
| Biological model | Reconstructed Epidermis, BIOalternatives RHE |
| Species | Human |
| Endpoint | 5- alpha reductase activity |
| Method | [14C]-testosterone incorporation |
| Stimulating factor / inducer | Basal |
| Reference compound | Finasteride |
| Physio-pathology | Hair growth & degeneration, Acne, Acne |
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Reference | Physio-pathology | Type of assay | Biological model | Species | Endpoint | Method | Stimulating factor / inducer | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
 NHDF, testosterone metabolism & 5- alpha reductase activity (basal)
| NHDF-0050 | Hair growth & degeneration, Acne, Acne | Androgen metabolism | Dermal fibroblasts (NHDF) | Human | 5- alpha reductase activity | [14C]-testosterone incorporation | Basal | |||||||||
 NHEK, testosterone metabolism & 5- alpha reductase activity (basal)
| NHEK-0124 | Hair growth & degeneration, Acne, Acne | Androgen metabolism | Epidermal keratinocytes (NHEK) | Human | 5- alpha reductase activity | [14C]-testosterone incorporation | Basal |
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