Online Catalogs
EPIBA-0022 - RHE, mRNA for differentiation markers (basal)
| Type of assay | Gene expression |
| Biological model | Reconstructed Epidermis, BIOalternatives RHE |
| Species | Human |
| Endpoint | mRNA: e.g. FLG, TGM1, KRT10, LOR…, mQPA-NHEK-16, mQPA-NHEK-32, mQPA-NHEK-64 |
| Method | RT-qPCR, qPCRarray (standard or customized) |
| Stimulating factor / inducer | Basal |
| Reference compound | Retinoic acid |
| Physio-pathology | Differentiation, protection, barrier function |
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Reference
Physio-pathology
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Reference | Physio-pathology | Type of assay | Biological model | Species | Endpoint | Method | Stimulating factor / inducer | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
 FTSK, mRNA for differentiation markers (basal)
| SKIBA-0002 | Differentiation, protection, barrier function | Gene expression | Full thickness reconstructed skin, BIOalternatives | Human | mRNA: e.g. FLG, TGM1, KRT10, LOR…, mQPA-NHEK-16, mQPA-NHEK-32, mQPA-NHEK-64 | RT-qPCR, qPCRarray (standard or customized) | Basal | |||||||||
Skin maintained ex vivo, mRNA for differentiation markers (basal)
| SKIN-0008 | Differentiation, protection, barrier function | Gene expression | Skin (ex vivo) | Human | mRNA: e.g. FLG, TGM1, KRT10, LOR…, mQPA-NHEK-16, mQPA-NHEK-32, mQPA-NHEK-64 | RT-qPCR, qPCRarray (standard or customized) | Basal | |||||||||
 NHEK, mRNA for differentiation markers (low calcium) (basal)
| NHEK-0062 | Differentiation, protection, barrier function | Gene expression | Epidermal keratinocytes (NHEK) | Human | mRNA: e.g. FLG, TGM1, KRT10…, mQPA-NHEK-16, mQPA-NHEK-32, mQPA-NHEK-64 | RT-qPCR, qPCRarray (standard or customized) | Basal | |||||||||
NHEK, mRNA for differentiation markers (high calcium, differentiation medium)
| NHEK-0125 | Differentiation, protection, barrier function | Gene expression | Epidermal keratinocytes (NHEK) | Human | mRNA: e.g. FLG, TGM1, KRT10…, mQPA-NHEK-16, mQPA-NHEK-32, mQPA-NHEK-64 | RT-qPCR, qPCRarray (standard or customized) | Calcium |
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