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You are viewing records 81-90 out of 491 total records on 50 pages

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RHE, gene expression + histology (cytokine stimulation)

EPIBA-0007 - RHE, gene expression + histology (cytokine stimulation)

Type of assay	Gene expression
Biological model	Reconstructed Epidermis, BIOalternatives RHE
Species	Human
Endpoint	Specific mRNA(s) + histology, mQPA-NHEK-PSO-16, mQPA-NHEK-PSO-32, mQPA-NHEK-PSO-64

RHE, gene expression (T cell medium stimulation)

EPIBA-0008 - RHE, gene expression (T cell medium stimulation)

Type of assay	Gene expression
Biological model	Reconstructed Epidermis, BIOalternatives RHE
Species	Human
Endpoint	mRNA: e.g. DEFB4, S100A7, CXCL8, KRT10,..., mQPA-NHEK-PSO-16, mQPA-NHEK-PSO-32, mQPA-NHEK-PSO-64

RHE, gene expression + histology (T cell medium stimulation)

EPIBA-0009 - RHE, gene expression + histology (T cell medium stimulation)

Type of assay	Gene expression
Biological model	Reconstructed Epidermis, BIOalternatives RHE
Species	Human
Endpoint	Specific mRNA(s) + histology, mQPA-NHEK-PSO-16, mQPA-NHEK-PSO-32, mQPA-NHEK-PSO-64

RHE, CPD determination (UV stimulation)

EPIBA-0010 - RHE, CPD determination (UV stimulation)

Type of assay	DNA damage/apoptosis
Biological model	Reconstructed Epidermis, BIOalternatives RHE
Species	Human
Endpoint	DNA cyclobutane pyrimidine dimers

RHE, skin innate immunity markers expression (Basal)

EPIBA-0048 - RHE, skin innate immunity markers expression (Basal)

Type of assay	Skin innate defense
Biological model	Reconstructed Epidermis, BIOalternatives RHE
Species	Human
Endpoint	Expression of e.g. S100A7, beta-defensin 2/4, RNAse7

RHE, IL-8 release (Basal)

EPIBA-0049 - RHE, IL-8 release (Basal)

Type of assay	Skin innate defense
Biological model	Reconstructed Epidermis, BIOalternatives RHE
Species	Human
Endpoint	IL-8 release

RHE, innate immunity gene expression (Basal)

EPIBA-0050 - RHE, innate immunity gene expression (Basal)

Type of assay	Skin innate defense
Biological model	Reconstructed Epidermis, BIOalternatives RHE
Species	Human
Endpoint	mRNA: e.g. DEFB4, S100A7, PI3, LL37, RNASE7,..., mQPA-NHEK-IMMUNITY-16

RHE, testosterone metabolism & 5- alpha reductase activity (basal)

EPIBA-0052 - RHE, testosterone metabolism & 5- alpha reductase activity (basal)

Type of assay	Androgen metabolism
Biological model	Reconstructed Epidermis, BIOalternatives RHE
Species	Human
Endpoint	5- alpha reductase activity

RHE, skin innate immunity markers expression (cytokine stimulation)

EPIBA-0057 - RHE, skin innate immunity markers expression (cytokine stimulation)

Type of assay	Protein markers
Biological model	Reconstructed Epidermis, BIOalternatives RHE
Species	Human
Endpoint	Expression of e.g. S100A7, beta-defensin 2/4, RNAse7

RHE, IL-8 release (cytokine stimulation)

EPIBA-0058 - RHE, IL-8 release (cytokine stimulation)

Type of assay	Protein markers
Biological model	Reconstructed Epidermis, BIOalternatives RHE
Species	Human
Endpoint	IL-8 release

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