3T3-L1, NEFA release (basal)| Type of assay | Triglyceride hydrolysis | | Biological model | 3T3-L1 preadipocyte cell line (adipocyte-differentiated) | | Species | Mouse | | Endpoint | Non-esterified fatty acid release |
| 3T3L1-0001 | Lipolysis, Lipolysis | Triglyceride hydrolysis | 3T3-L1 preadipocyte cell line (adipocyte-differentiated) | Mouse | Non-esterified fatty acid release | Photometry | Basal | |
3T3-L1, lipid neosynthesis (basal)| Type of assay | Lipogenesis | | Biological model | 3T3-L1 preadipocyte cell line (adipocyte-differentiated) | | Species | Mouse | | Endpoint | Lipid neosynthesis |
| 3T3L1-0004 | Lipogenesis, fat storage, Lipogenesis, fat storage | Lipogenesis | 3T3-L1 preadipocyte cell line (adipocyte-differentiated) | Mouse | Lipid neosynthesis | [14C]-acetate incorporation | Basal | |
3T3-L1, lipid neosynthesis (basal)| Type of assay | Lipogenesis | | Biological model | 3T3-L1 preadipocyte cell line (adipocyte-differentiated) | | Species | Mouse | | Endpoint | Lipid neosynthesis |
| 3T3L1-0005 | Lipogenesis, fat storage, Lipogenesis, fat storage | Lipogenesis | 3T3-L1 preadipocyte cell line (adipocyte-differentiated) | Mouse | Lipid neosynthesis | [3H]-glucose incorporation | Basal | |
3T3-L1, lipid neosynthesis (basal)| Type of assay | Lipogenesis | | Biological model | 3T3-L1 preadipocyte cell line (adipocyte-differentiated) | | Species | Mouse | | Endpoint | Fatty acid uptake |
| 3T3L1-0006 | Lipogenesis, fat storage, Lipogenesis, fat storage | Lipogenesis | 3T3-L1 preadipocyte cell line (adipocyte-differentiated) | Mouse | Fatty acid uptake | [14C]-oleate incorporation | Basal | |
3T3-L1, active lipoprotein lipase (LPL) production (basal)| Type of assay | Lipogenesis | | Biological model | 3T3-L1 preadipocyte cell line (adipocyte-differentiated) | | Species | Mouse | | Endpoint | Synthesis / release of active LPL |
| 3T3L1-0008 | Lipogenesis, fat storage, Lipogenesis, fat storage | Lipogenesis | 3T3-L1 preadipocyte cell line (adipocyte-differentiated) | Mouse | Synthesis / release of active LPL | Radioactivity | Basal | |
3T3-L1, differentiation, lipid content/analysis| Type of assay | Morphological changes/lipid accumulation | | Biological model | 3T3-L1 preadipocyte cell line | | Species | Mouse | | Endpoint | Lipid labeling |
| 3T3L1-0010 | Adipocyte differentiation, Adipocyte differentiation | Morphological changes/lipid accumulation | 3T3-L1 preadipocyte cell line | Mouse | Lipid labeling | Fluorescence / imaging | Differentiation mix | |
AoSMC, veinotonic activity (basal)| Type of assay | | | Biological model | Aortic smooth muscle cells (AoSMC) | | Species | Human | | Endpoint | Calcium mobilization |
| AOSMC-0001 | Vascularization | | Aortic smooth muscle cells (AoSMC) | Human | Calcium mobilization | Time-lapse microscopy | Basal | |
B16, stimulation of melanin synthesis (basal, pro-pigmenting agents)| Type of assay | Melanin synthesis | | Biological model | B16 melanoma cell line | | Species | Mouse | | Endpoint | Melanin content |
| B16-0001 | Melanogenesis, Pigmentation disorders | Melanin synthesis | B16 melanoma cell line | Mouse | Melanin content | Photometry | Basal | |
B16, inhibition of melanin synthesis (MSH-induced, whitening agents)| Type of assay | Melanin synthesis | | Biological model | B16 melanoma cell line | | Species | Mouse | | Endpoint | Melanin content |
| B16-0002 | Melanogenesis, Pigmentation disorders | Melanin synthesis | B16 melanoma cell line | Mouse | Melanin content | Photometry | NDP-MSH | |
B16, tyrosinase expression (basal)| Type of assay | Melanogenic proteins | | Biological model | B16 melanoma cell line | | Species | Mouse | | Endpoint | Tyrosinase immunolabeling |
| B16-0010 | Melanogenesis, Pigmentation disorders | Melanogenic proteins | B16 melanoma cell line | Mouse | Tyrosinase immunolabeling | Immunofluorescence | Basal | |
B16, tyrosinase expression (MSH stimulation)| Type of assay | Melanogenic proteins | | Biological model | B16 melanoma cell line | | Species | Mouse | | Endpoint | Tyrosinase immunolabeling |
| B16-0011 | Melanogenesis, Pigmentation disorders | Melanogenic proteins | B16 melanoma cell line | Mouse | Tyrosinase immunolabeling | Immunofluorescence | NDP-MSH | |
B16, TRP-1 expression (basal)| Type of assay | Melanogenic proteins | | Biological model | B16 melanoma cell line | | Species | Mouse | | Endpoint | TRP-1 immunolabeling |
| B16-0012 | Melanogenesis, Pigmentation disorders | Melanogenic proteins | B16 melanoma cell line | Mouse | TRP-1 immunolabeling | Immunofluorescence | Basal | |
B16, TRP-1 expression (MSH stimulation)| Type of assay | Melanogenic proteins | | Biological model | B16 melanoma cell line | | Species | Mouse | | Endpoint | TRP-1 expression |
| B16-0013 | Melanogenesis, Pigmentation disorders | Melanogenic proteins | B16 melanoma cell line | Mouse | TRP-1 expression | Immunofluorescence | NDP-MSH | |
B16, tyrosinase activity (basal)| Type of assay | Melanogenic proteins | | Biological model | B16 melanoma cell line | | Species | Mouse | | Endpoint | Tyrosinase activity |
| B16-0014 | Melanogenesis, Pigmentation disorders | Melanogenic proteins | B16 melanoma cell line | Mouse | Tyrosinase activity | Photometry | Basal | |
B16, pigmentation-related gene expression (basal)| Type of assay | Gene expression | | Biological model | B16 melanoma cell line | | Species | Mouse | | Endpoint | mRNA: e.g. TYR, TRP1, TRP2, MITF, MC1R,..., mQPA-B16-16, mQPA-B16-64 |
| B16-0016 | Melanogenesis, Pigmentation disorders | Gene expression | B16 melanoma cell line | Mouse | mRNA: e.g. TYR, TRP1, TRP2, MITF, MC1R,..., mQPA-B16-16, mQPA-B16-64 | RT-qPCR, qPCRarray (standard or customized) | Basal | |
B16, pigmentation-related gene expression (MSH stimulation)| Type of assay | Gene expression | | Biological model | B16 melanoma cell line | | Species | Mouse | | Endpoint | mRNA: e.g. TYR, TRP1, TRP2, MITF, MC1R,..., mQPA-B16-16, mQPA-B16-64 |
| B16-0018 | Melanogenesis, Pigmentation disorders | Gene expression | B16 melanoma cell line | Mouse | mRNA: e.g. TYR, TRP1, TRP2, MITF, MC1R,..., mQPA-B16-16, mQPA-B16-64 | RT-qPCR, qPCRarray (standard or customized) | NDP-MSH | |
MMP-1 inhibition (recombinant enzyme)| Type of assay | Enzyme activity | | Biological model | Acellular | | Species | Human | | Endpoint | Human MMP-1 activity |
| BIOCH-0002 | Enzyme activity assays, ECM degradation | Enzyme activity | Acellular | Human | Human MMP-1 activity | Fluorescence | | |
MMP-9 inhibition (recombinant enzyme)| Type of assay | Enzyme activity | | Biological model | Acellular | | Species | Human | | Endpoint | Human MMP-9 activity |
| BIOCH-0003 | Enzyme activity assays, ECM degradation | Enzyme activity | Acellular | Human | Human MMP-9 activity | Fluorescence | | |
MMP inhibition (NHDF extracts)| Type of assay | Enzyme activity | | Biological model | Acellular | | Species | Human | | Endpoint | Human MMP activity (2 substrates)*, Human MMP-2 and MMP-7 activity, Human MMP-1, MMP-8, MMP-13 and MMP-14 activity |
| BIOCH-0004 | Enzyme activity assays, ECM degradation | Enzyme activity | Acellular | Human | Human MMP activity (2 substrates)*, Human MMP-2 and MMP-7 activity, Human MMP-1, MMP-8, MMP-13 and MMP-14 activity | Fluorescence | | |
Hyaluronidase inhibition (purified enzyme)| Type of assay | Enzyme activity | | Biological model | Acellular | | Species | Bovine | | Endpoint | Hyaluronidase activity |
| BIOCH-0005 | Enzyme activity assays, Epidermal matrix, hydration, ECM degradation | Enzyme activity | Acellular | Bovine | Hyaluronidase activity | Photometry | Basal | |
