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You are viewing records 1-20 out of 326 total records on 17 pages
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Plus d'options Reference Physio-pathology Type of assay Biological model Species Endpoint Method Stimulating factor / inducer
B16, stimulation of melanin synthesis (basal, pro-pigmenting agents)

B16, stimulation of melanin synthesis (basal, pro-pigmenting agents)

Type of assayMelanin synthesis
Biological modelB16 melanoma cell line
SpeciesMouse
EndpointMelanin content
B16-0001Melanogenesis, Pigmentation disordersMelanin synthesisB16 melanoma cell lineMouseMelanin contentPhotometryBasal
B16, inhibition of melanin synthesis (MSH-induced, whitening agents)

B16, inhibition of melanin synthesis (MSH-induced, whitening agents)

Type of assayMelanin synthesis
Biological modelB16 melanoma cell line
SpeciesMouse
EndpointMelanin content
B16-0002Melanogenesis, Pigmentation disordersMelanin synthesisB16 melanoma cell lineMouseMelanin contentPhotometryNDP-MSH
B16, tyrosinase expression (basal)

B16, tyrosinase expression (basal)

Type of assayMelanogenic proteins
Biological modelB16 melanoma cell line
SpeciesMouse
EndpointTyrosinase immunolabeling
B16-0010Melanogenesis, Pigmentation disordersMelanogenic proteinsB16 melanoma cell lineMouseTyrosinase immunolabelingImmunofluorescenceBasal
B16, tyrosinase expression (MSH stimulation)

B16, tyrosinase expression (MSH stimulation)

Type of assayMelanogenic proteins
Biological modelB16 melanoma cell line
SpeciesMouse
EndpointTyrosinase immunolabeling
B16-0011Melanogenesis, Pigmentation disordersMelanogenic proteinsB16 melanoma cell lineMouseTyrosinase immunolabelingImmunofluorescenceNDP-MSH
B16, TRP-1 expression (basal)

B16, TRP-1 expression (basal)

Type of assayMelanogenic proteins
Biological modelB16 melanoma cell line
SpeciesMouse
EndpointTRP-1 immunolabeling
B16-0012Melanogenesis, Pigmentation disordersMelanogenic proteinsB16 melanoma cell lineMouseTRP-1 immunolabelingImmunofluorescenceBasal
B16, TRP-1 expression (MSH stimulation)

B16, TRP-1 expression (MSH stimulation)

Type of assayMelanogenic proteins
Biological modelB16 melanoma cell line
SpeciesMouse
EndpointTRP-1 expression
B16-0013Melanogenesis, Pigmentation disordersMelanogenic proteinsB16 melanoma cell lineMouseTRP-1 expressionImmunofluorescenceNDP-MSH
B16, tyrosinase activity (basal)

B16, tyrosinase activity (basal)

Type of assayMelanogenic proteins
Biological modelB16 melanoma cell line
SpeciesMouse
EndpointTyrosinase activity
B16-0014Melanogenesis, Pigmentation disordersMelanogenic proteinsB16 melanoma cell lineMouseTyrosinase activityPhotometryBasal
B16, pigmentation-related gene expression (basal)

B16, pigmentation-related gene expression (basal)

Type of assayGene expression
Biological modelB16 melanoma cell line
SpeciesMouse
EndpointmRNA: e.g. TYR, TRP1, TRP2, MITF, MC1R,..., qPCRarray (16 genes)
B16-0016Melanogenesis, Pigmentation disordersGene expressionB16 melanoma cell lineMousemRNA: e.g. TYR, TRP1, TRP2, MITF, MC1R,..., qPCRarray (16 genes)RT-qPCR, qPCRarray (standard or customized)Basal
B16, pigmentation-related gene expression (MSH stimulation)

B16, pigmentation-related gene expression (MSH stimulation)

Type of assayGene expression
Biological modelB16 melanoma cell line
SpeciesMouse
EndpointmRNA: e.g. TYR, TRP1, TRP2, MITF, MC1R,..., qPCRarray (16 genes)
B16-0018Melanogenesis, Pigmentation disordersGene expressionB16 melanoma cell lineMousemRNA: e.g. TYR, TRP1, TRP2, MITF, MC1R,..., qPCRarray (16 genes)RT-qPCR, qPCRarray (standard or customized)NDP-MSH
Acellular, free radical scavenging

Acellular, free radical scavenging

Type of assayFree radicals
Biological model
Species
EndpointDPPH
BIOCH-0007UV, solar, free radicals, sunburn, Miscellaneous free radicals assays, UV, solar, sunburn (epidermis)Free radicalsDPPHPhotometry
Acellular, free radical scavenging

Acellular, free radical scavenging

Type of assayFree radicals
Biological model
Species
EndpointH2O2 measurement (Amplex Red)
BIOCH-0008UV, solar, free radicals, sunburn, Miscellaneous free radicals assays, UV, solar, sunburn (epidermis)Free radicalsH2O2 measurement (Amplex Red)Fluorescence
Acellular, free radical scavenging

Acellular, free radical scavenging

Type of assayFree radicals
Biological model
Species
EndpointORAC
BIOCH-0009UV, solar, free radicals, sunburn, Miscellaneous free radicals assays, UV, solar, sunburn (epidermis)Free radicalsORACPhotometry
Tyrosinase inhibition (mushroom enzyme)

Tyrosinase inhibition (mushroom enzyme)

Type of assayTyrosinase inhibition
Biological model
Species
EndpointTyrosinase activity
BIOCH-0010Enzyme activity assays, Melanogenesis, Pigmentation disordersTyrosinase inhibitionTyrosinase activityPhotometry
Tyrosinase inhibition (NHEM extract)

Tyrosinase inhibition (NHEM extract)

Type of assayTyrosinase inhibition
Biological model
SpeciesHuman
EndpointTyrosinase activity
BIOCH-0011Enzyme activity assays, Melanogenesis, Pigmentation disordersTyrosinase inhibitionHumanTyrosinase activityPhotometry
COX-2, enzymatic activity

COX-2, enzymatic activity

Type of assayArachidonic acid metabolites
Biological model
SpeciesHuman
EndpointCOX-2 activity
BIOCH-0017Enzyme activity assays, Enzyme inhibition assaysArachidonic acid metabolitesHumanCOX-2 activityELISA / EIA
LOX-5, enzymatic activity

LOX-5, enzymatic activity

Type of assayArachidonic acid metabolites
Biological model
SpeciesHuman
EndpointLOX-5 activity
BIOCH-0018Enzyme activity assays, Enzyme inhibition assaysArachidonic acid metabolitesHumanLOX-5 activityFluorescence
Caspase 3/7, enzymatic activity

Caspase 3/7, enzymatic activity

Type of assayApoptosis
Biological model
SpeciesHuman
EndpointCaspase 3/7 activity
BIOCH-0019Enzyme activity assays, Photo-aging (dermis), Photo-aging, UV, solar (dermis)ApoptosisHumanCaspase 3/7 activityFluorescence
TBARS formation

TBARS formation

Type of assayFree radicals
Biological model
Species
EndpointTBARS production
BIOCH-0025UV, solar, free radicals, sunburn, Miscellaneous free radicals assays, UV, solar, sunburn (epidermis)Free radicalsTBARS productionPhotometryFeSO4
Caspase 1, enzymatic activity

Caspase 1, enzymatic activity

Type of assayEnzyme activity
Biological model
SpeciesHuman
EndpointCaspase-1 activity
BIOCH-0034Enzyme activity assays, Wound healing, trauma & agressions, Wound healing, trauma & aggressionsEnzyme activityHumanCaspase-1 activityFluorescence
Blood, CD11b/CD62L expression (TNF- alpha stimulation)

Blood, CD11b/CD62L expression (TNF- alpha stimulation)

Type of assayActivation markers
Biological modelWhole Blood
SpeciesHuman
EndpointCD11b (increase) / CD62L (decrease) expression
BLOO-0001Granulocytes, Granulocytes: inflammation & host defenseActivation markersWhole BloodHumanCD11b (increase) / CD62L (decrease) expressionFlow cytometryTNF- alpha
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