CD4TL-0001 : CD4+ T cells, cytokine release (anti-CD3/anti-CD28 stimulation)

  • Cell Model :

    CD4+ T cells

  • Source :

    Human

  • Parameter/biomarker/endpoint :

    IFN- gamma release

  • Method :

    ELISA

  • Stimulating factor/inducer :

    Anti-CD3/anti-CD28

  • Reference compound :

    Cyclosporin A

Physio-pathology :

  • T lymphocytes: anti-inflammatory effects/immunosuppression - cell-mediated and humoral immunity modulation

  • Type of assay :

    Th1 polarity - Cytokines