NS-0002 : Sensory neurons, calcium mobilization (histamine stimulation)

  • Cell Model :

    Sensory neurons

  • Source :

    Rat

  • Parameter/biomarker/endpoint :

    Calcium mobilization

  • Method :

    Time-lapse microscopy

  • Stimulating factor/inducer :

    Histamine

  • Reference compound :

    Chlorpheniramine

Physio-pathology :

  • Pruritus, itching
  • Peripheral inflammation, sensitivity, pain, itching
  • Sensitive skin

  • Type of assay :

    Signal transduction