Ischemia & Stroke
NCOR-0001 : Cortical neurons, neurite outgrowth (basal)
- Cell Model :
Cortical neurons
- Parameter/biomarker/endpoint :
beta-III tubulin labeling
- Method :
Immunofluorescence
- Stimulating factor/inducer :
Basal
- Reference compound :
FCS
Control
FCS-stimulated
NCOR-0002 : Cortical neuron network (glutamate-intoxicated)
- Cell Model :
Cortical neurons
- Parameter/biomarker/endpoint :
NF-H labeling
- Method :
Immunofluorescence
- Stimulating factor/inducer :
Glutamate
- Reference compound :
MK-801
Control
Glutamate-intoxicated
NCOR-0004 : Cortical neuron network (O2-deprivated)
- Cell Model :
Cortical neurons + astrocytes
- Parameter/biomarker/endpoint :
MAP-2 labeling
- Method :
Immunofluorescence
- Stimulating factor/inducer :
O2 deprivation
- Reference compound :
NGF
Control
O2-deprivated
NCOR-0005 : Cortical neuron network (glucose-deprivated)
- Cell Model :
Cortical neurons + astrocytes
- Parameter/biomarker/endpoint :
MAP-2 labeling
- Method :
Immunofluorescence
- Stimulating factor/inducer :
Glucose deprivation
- Reference compound :
NGF
Control
NCOR-0006 : Cortical neuron network (O2 and glucose-deprivated)
- Cell Model :
Cortical neurons + astrocytes
- Parameter/biomarker/endpoint :
beta-III tubulin labeling
- Method :
Immunofluorescence
- Stimulating factor/inducer :
O2 and glucose deprivation
- Reference compound :
NGF
Cortical neurons
NCOR-0007 : Cortical neuron network (H2O2-intoxicated)
- Cell Model :
Cortical neurons + astrocytes
- Parameter/biomarker/endpoint :
beta-III tubulin labeling
- Method :
Immunofluorescence
- Stimulating factor/inducer :
H2O2
- Reference compound :
NGF
Cortical neurons
NHIPP-0004 : Hippocampal neuron network (glutamate-intoxicated)
- Cell Model :
Hippocampal neurons
- Parameter/biomarker/endpoint :
NF-H labeling
- Method :
Immunofluorescence
- Stimulating factor/inducer :
Glutamate
- Reference compound :
MK-801
Control
Glutamate-intoxicated
NMOT-0001 : Motoneuron network (glutamate-intoxicated)
- Cell Model :
Motoneurons
- Parameter/biomarker/endpoint :
NF-H labeling
- Method :
Immunofluorescence
- Stimulating factor/inducer :
Glutamate
- Reference compound :
Riluzole
Control
Glutamate-intoxicated
PC12-0001 : PC12, neurite outgrowth (basal)
- Cell Model :
PC12 neuroblastoma cell line
- Parameter/biomarker/endpoint :
NF-H labeling
- Method :
Immunofluorescence
- Stimulating factor/inducer :
Basal
- Reference compound :
NGF
Control
NGF-stimulated
