Vascularization
AOSMC-0001 : AoSMC, veinotonic activity (basal)
- Cell Model :
Aortic smooth muscle cells
- Parameter/biomarker/endpoint :
Calcium mobilization
- Method :
Time-lapse microscopy
- Stimulating factor/inducer :
Basal
- Reference compound :
Bradykinin
Calcium mobilization
HUVEC-0001 : HUVEC, ICAM-1 expression (TNF- alpha stimulation)
- Cell Model :
Umbilical vein endothelial cells
- Parameter/biomarker/endpoint :
ICAM-1 immunolabeling
- Method :
Fluorescence / imaging
- Stimulating factor/inducer :
TNF- alpha
Labeling
ICAM-1
HUVEC-0006 : HUVEC, ICAM-1 expression (TNF- alpha stimulation)
- Cell Model :
Umbilical vein endothelial cells
- Parameter/biomarker/endpoint :
qPCRarray (16 genes)
- Method :
RT-qPCR
- Stimulating factor/inducer :
TNF- alpha
NHEK-0116 : NHEK, thrombospondin 1 (THBS1) production (basal)
- Cell Model :
Epidermal keratinocytes
- Parameter/biomarker/endpoint :
THBS1 synthesis
- Method :
ELISA
- Reference compound :
LL-37
THBS1 production
