HL60-0002 : HL-60, arachidonic acid metabolite release (A23187 stimulation)

  • Cell Model :

    HL-60 (vitD3/TGF- beta-differentiated)

  • Source :

    Human

  • Parameter/biomarker/endpoint :

    LTB4 release

  • Method :

    ELISA

  • Stimulating factor/inducer :

    Ionophore A23187

  • Reference compound :

    AA861

Physio-pathology :

  • Selection of basic/robust inflammation assays for screening (human cell lines)
  • Monocytes/macrophages: inflammation, innate immunity

  • Type of assay :

    Arachidonic mediators