Arachidonic mediators

HL60-0002 : HL-60, arachidonic acid metabolite release (A23187 stimulation)

  • Cell Model :

    HL-60 (vitD3/TGF- beta-differentiated)

  • Parameter/biomarker/endpoint :

    LTB4 release

  • Method :

    ELISA

  • Stimulating factor/inducer :

    Ionophore A23187

  • Reference compound :

    AA861


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NCTC-0002 : NCTC 2544, PGE2 release (PMA stimulation)

  • Cell Model :

    NCTC 2544 cell line

  • Parameter/biomarker/endpoint :

    PGE2 release

  • Method :

    ELISA

  • Stimulating factor/inducer :

    PMA

  • Reference compound :

    Indomethacin


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U937-0002 : U-937, arachidonic acid metabolite release (LPS stimulation)

  • Cell Model :

    U-937 (PMA-differentiated)

  • Parameter/biomarker/endpoint :

    PGE2 release

  • Method :

    ELISA

  • Stimulating factor/inducer :

    LPS

  • Reference compound :

    Indomethacin


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