NCTC-0002 : NCTC 2544, PGE2 release (PMA stimulation)

  • Cell Model :

    NCTC 2544 cell line

  • Source :

    Human

  • Parameter/biomarker/endpoint :

    PGE2 release

  • Method :

    ELISA

  • Stimulating factor/inducer :

    PMA

  • Reference compound :

    Indomethacin

Physio-pathology :

  • Selection of basic/robust inflammation assays for screening (human cell lines)
  • Keratinocyte response to small bioactive molecules
  • Keratinocyte inflammatory response to small bioactive molecules

  • Type of assay :

    Arachidonic mediators