https://cdn-bneoicczbswi.netdna-ssl.com/wp-content/uploads/2017/08/Mouse-epidermis.png 368 655 Linhda Coulevard https://www.bioalternatives.com/wp-content/uploads/2017/03/logo-Bioalternatives-1.png Linhda Coulevard2017-06-26 09:52:152017-08-31 08:26:26Development of a new model of reconstituted mouse epidermis and characterization of its response to proinflammatory cytokines
The development of three-dimensional models of reconstituted mouse epidermis (RME) has been hampered by the difficulty to maintain murine primary keratinocyte cultures and to achieve a complete epidermal stratification. In this study, a new protocol is proposed for the rapid and convenient generation of RME,
https://cdn-bneoicczbswi.netdna-ssl.com/wp-content/uploads/2017/03/Silab-Image-à-la-une.jpg 350 623 Linhda Coulevard https://www.bioalternatives.com/wp-content/uploads/2017/03/logo-Bioalternatives-1.png Linhda Coulevard2017-03-21 18:10:582017-03-23 12:14:32in vitro modeling of skin photoaging: development of evaluation tools for cosmetics
Development of in vitro models skin for better understand the modifications during photo-aging induced by repetitive UV exposure.
https://cdn-bneoicczbswi.netdna-ssl.com/wp-content/uploads/2016/12/Epiderme-reconstruit-passage-2-figure-1A-1.jpg 368 655 Guillaume https://www.bioalternatives.com/wp-content/uploads/2017/03/logo-Bioalternatives-1.png Guillaume2016-12-21 16:21:562016-12-29 11:57:19Development of a new model of reconstructed aged skin useful to study Antiageing effects of cosmetic compounds
The development of new anti-aging products needs performant in vitro models mimicking morphological changes and physiological modifications appearing during skin aging. In order to have access to a simple model mimicking the epidermis ageing but in relation with a normal dermis, we have developed a new in vitro model of reconstructed skin comprising an aged epidermis covering a reconstructed dermis built with collagen and normal (young) fibroblasts.
https://cdn-bneoicczbswi.netdna-ssl.com/wp-content/uploads/2016/03/mw_androgens-induce-sebaceous-differentiation-in-sebocyte.jpg 368 655 Julie https://www.bioalternatives.com/wp-content/uploads/2017/03/logo-Bioalternatives-1.png Julie2015-04-09 15:47:492016-12-29 11:58:19Androgens induce sebaceous differentiation in sebocyte cells expressing a stable functional androgen receptor
https://cdn-bneoicczbswi.netdna-ssl.com/wp-content/uploads/2016/05/mw_Immortalized-sebocytes.jpg 368 655 Julie https://www.bioalternatives.com/wp-content/uploads/2017/03/logo-Bioalternatives-1.png Julie2012-01-24 10:17:152016-12-29 11:58:26Immortalized sebocytes SEB0662 can spontaneously differentiate into a sebaceous-like phenotype when cultured as a 3D epithelium
SEBO662 multilayers spontaneously differentiate into a sebaceous-like structure as shown by the strong polarized expression of the late sebaceous marker EMA, the overexpression of some lipogenic markers and lipid production on the upper side of the epithelium.
https://cdn-bneoicczbswi.netdna-ssl.com/wp-content/uploads/2016/05/mw_Human-embryonic-stem-cell-derivatives.jpg 368 655 Julie https://www.bioalternatives.com/wp-content/uploads/2017/03/logo-Bioalternatives-1.png Julie2009-11-21 15:43:332016-12-29 12:00:44Human embryonic stem-cell derivatives for full reconstruction of the pluristratified epidermis: a preclinical study
To assess whether the keratinocyte progeny of human embryonic stem cells (hESCs) could be used to form a temporary skin substitute for use in patients awaiting autologous grafts, we investigated the cells' capability of constructing a pluristratified epidermis.