Abstract

In addition to the natural process of skin aging, the skin of women is significantly impacted during and after menopause. In post-menopausal women, the effect of oestrogen deprivation results in decreased collagen synthesis leading to skin atrophy, in reduced skin elasticity and in increased skin dryness. The aim of the present study was to assess the benefit of a fixed compensating skin care topical serum complex, containing the C-xylopyranoside derivative proxylane at 3%, hedione 1%, hydrovance and hepes 5% each (Laboratoires Vichy, Asnières sur Seine, France) and a moisturising cream (containing water, glycerin, cyclohexasiloxane, stearic acid, butylene glycol) versus the moisturizing cream alone during 60 days of daily application in post-menopausal women.