Acne vulgaris: Origins, symptoms and current treatments
The environmental component
The presence of bacteria such as Propionibacterium acnes in the pilosebaceous structure is acknowledged as being implicated in the development of the disease. Heavy smoking and alcohol consumption also appear to be factors which may increase the acne condition. Among other environmental factors, stress, urban pollution and exposure to the sun (UV radiation inducing sebum peroxidation), are also recognized as being implicated in the exacerbation of acne symptoms.
Complications may occur in certain cases. The onset of sometimes painful nodules and cysts is one of the very severe forms of acne which will lead to deep scarring and hyperpigmentation. Certain bacteria (Propionibacterium acnes, Staphylococcus aureus, etc.) are well known for their implication in the exacerbation of the disease.
The currently used anti-acne treatments are mainly designed to reduce the onset of the clinical signs (Figure 3). At the present time, there is no treatment which can prevent and effectively treat this pathology.