Increased fatty acid synthesis inhibits nitrogen starvation-induced autophagy in lipid droplet-deficient yeast
Cerulenin, a potent inhibitor of fatty acid synthase, and exogenous addition of palmitic acid could restore nitrogen-starvation induced autophagy in the absence of lipid droplets.
Oncostatin M is overexpressed in skin squamous-cell carcinoma and promotes tumor progression
Cutaneous squamous cell carcinoma (cSCC) is the second most common keratinocyte malignancy and accounts for 20% of skin cancer deaths.
Anti-inflammatory activity of CKC-containing cationic emulsion eye drop vehicles
Preservative-free cationic emulsion-based artificial tears (ATs) or drug vehicles are innovative eye drop formulations with tear film stabilization and drug delivery properties, and valuable in vivo anti-inflammatory and wound healing properties.
Contribution of IL22 to experimental skin inflammation
Focused on in vitro human models, we present the mechanisms of action of IL22 as well as its involvement in structure, metabolism, differentiation, chemotaxis, antibacterial activity, innate immunity, and tissue remodeling of epidermis.
Human embryonic stem-cell derivatives for full reconstruction of the pluristratified epidermis: a preclinical study
To assess whether the keratinocyte progeny of human embryonic stem cells (hESCs) could be used to form a temporary skin substitute for use in patients awaiting autologous grafts, we investigated the cells' capability of constructing a pluristratified epidermis.
Cultured keratinocyte cells from foreskin and future application for burns in children
The keratinocytes resulting from foreskin have a high capacity of division. These cells can divide a long time before differentiation. The observations enable us to propose with our patients the keratinocytes from foreskin for wound healing especially for burns in children.
